Phentermine for Weight Loss: Benefits, Side Effects, and Dosage

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​Phentermine is one of the most popular prescription medications used in weight loss. It stimulates the central nervous system and suppresses appetite while increasing metabolic rate by about three times.


The drug was initially approved in 1959, but it has been around for a lot longer than that. Phentermine was actually made from amphetamine in the late 1930s to help with diseases like narcolepsy and depression. This didn't pan out because of its side effects, so it wasn't brought into further study until 1954 when an FDA study deemed it safe enough to be studied as a weight loss medication


In 1959, Phentermine hydrochloride became available for use as a short-term pharmaceutical obesity treatment option under the trade name "Ionamin." It was available as tablets only, the first prescription diet drug to be approved by the U.S. Food and Drug Administration (FDA)


The FDA has required several safety warnings for phentermine's use over the years, both due to cardiovascular side effects and for patients with a history of heart conditions or psychological disorders. Despite this risk, phentermine remains one of the most popular weight loss medications in the United States today


Before starting any weight loss plan, it is important to talk with your doctor about health conditions you have now or have had in the past which could affect whether you are able to take Phentermine safely. This includes things like high blood pressure, glaucoma, bipolar disorder, a history of drug addiction, heart disease including any previous heart attack or stroke, uncontrolled hyperthyroidism (in the case of patients with an overactive thyroid gland), narrow-angle glaucoma or any allergies


Below are some specific points to consider before you start taking phentermine:



Phentermine is generally recommended for use by obese patients whose weight has been confirmed by at least two different methods. Your doctor must confirm that you have a body mass index (BMI) of 30 and above, and your overall wellbeing should be confirmed by your primary care physician and at least one other medical professional.



If you take more than the prescribed amount on a regular basis, there will likely be increased chances of side effects. If you take more than 60 milligrams in a day, there is also a greater risk of negative side effects.



When you first start taking Phentermine, the drug may cause increased heart rate and blood pressure in some people. It can also cause insomnia. These side effects should pass by the end of the second week.



You should not be on any other weight-loss medications when taking phentermine due to potentially serious complications from interactions between drugs.



Phentermine may have adverse psychological or mental health effects


Those who have a history of bipolar disorder or depression are advised against using Phentermine since they could worsen these conditions. In addition, those with a history of seizures should avoid taking this medication.



Because Phentermine works by suppressing appetite and raising metabolism, it is important that you do not take this drug when you are following a crash diet or severely restricting your calorie intake.



Phentermine should only be used to safely lose weight for two or three months at a time maximum. After that, you will need to stop taking the medication for several weeks before using again.



It is possible to experience rebound effects of Phentermine if the medication is discontinued suddenly. During this rebound period, some people may experience increased cravings for food, depression or apathy about exercising, anxiety issues or even tremors. Patients are advised against abruptly stopping phentermine use without talking with their doctor first.



As with all medications, there are possible side effects associated with phentermine. Some of these include increased appetite, insomnia, headache, dry mouth , dizziness and heart palpitations.



Keep in mind that not everyone experiences side effects when they take phentermine. Since this medication is classified by the FDA as a controlled substance due to its addictive properties, you should only begin taking it after discussing the possible negative consequences with your doctor.



Phentermine can interact negatively with certain medications or supplements; some examples are listed below:


You should definitely avoid Phentermine if you are allergic to any of its inactive ingredients (this also includes lactose )


When taken at high doses over time, some research has shown that phentermine may increase risk for developing cardiovascular disease or having a heart attack.



Phentermine should not be taken during pregnancy


If you are breastfeeding , your doctor may choose to prescribe Phentermine with cautious optimism based on your individualized medical history. If the benefits outweigh any potential risk, it is usually recommended that breastfeeding stop at least 3 weeks before starting phentermine use and resume at least three weeks after finishing the course of medication.



When taking Phentermine, there are certain things to avoid in order to prevent negative interactions. These include grapefruit juice , herbal supplements like St John's Wort , antidepressants including MAOIs (monoamine oxidase inhibitors), SSRIs (selective serotonin reuptake inhibitors) and tricyclics , selegiline, other diet medications , MAOIs (monoamine oxidase inhibitors), SSRIs (selective serotonin reuptake inhibitors), or tricyclic antidepressants.



It is also not recommended to combine Phentermine with another weight loss medication while taking. Instead, simply take one drug at a time, allowing the effects to build before adding in a second anti-obesity medication.



Phentermine can activate a psychological dependence that could lead to an addiction if the patient takes it for more than two months . It should be used only occasionally for this reason.



In Summary:


In conclusion, phentermine can be effective in aiding weight loss; however this medication is not appropriate for long-term use. Furthermore, it is important that you avoid combining phentermine with other drugs or medications while taking. If you are taking the medication only occasionally to shed pounds , then there should not be any adverse side effects, but if you are using Phentermine for more than three months at a time, then you need to consult your doctor about possible risks associated with phentermine use.



It's also very important to remember that everyone reacts differently to different types of medications , so do not take my analysis as the definitive answer regarding your questions regarding phentermine use! Make sure to consult your doctor before beginning any new medication regimen.
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